It's said here
http://www.nobaloney.net/downloads/...1/ReadMe-SpamBlockerVersion-4.1.exim.conf.txt :
WARNING: The following files must exist and have the same ownership
and permisssions as your /etc/virtual/domains file.
/etc/virtual/bad_sender_hosts
/etc/virtual/bad_sender_hosts_ip
/etc/virtual/blacklist_domains
/etc/virtual/blacklist_senders
/etc/virtual/whitelist_domains
/etc/virtual/whitelist_hosts
/etc/virtual/whitelist_hosts_ip
/etc/virtual/whitelist_senders
/etc/virtual/use_rbl_domains
/etc/virtual/skip_av_domains
/etc/virtual/skip_rbl_domains
Some of the above files may already exist and be populated.
If you have a prepopulated bad_sender_hosts file and if
it's populated with listings which consist of IP#s, then those
listings must be moved out of the bad_sender_hosts file and
into the bad_sender_hosts_ip file.