If I'm understanding your correctly... You can it just has to be setup through the nameserver pages with a ns.domain.com to it so that it knows that is supposed to respond to nameserver queries on that ip address.
For exmple say I have 2 ip address and the first is my server ip (base ip).
192.168.0.1 and 192.168.0.2
As long as I set it up to be ns1 and ns2.domain.com respectively you can use your base ip as a nameserver.
It just doesn't use any ips for nameservers as a default.